Abstract

Extraskeletal osteosarcoma is a rare malignant soft tissue tumor. Here we present a case of a primary extraskeletal osteosarcoma arising from omentum majus in a 40-year-old Chinese woman. Ultrasonography of the pelvic cavity showed a large soft tissue mass with marked calcification. Complete surgical resection of the primary tumor was performed and the histopathological diagnosis was extraskeletal osteosarcoma of omentum majus. She was followed up without adjuvant radiotherapy and chemotherapy, and died from widespread intra-abdominal, lung and liver metastases 7 months postoperatively.

Highlights

  • Extraskeletal osteosarcoma (ESOS) is a rare malignant mesenchymal neoplasm in soft tissues but not directly attached to the skeletal system

  • We describe a case of a primary ESOS arising from omentum majus

  • ESOS is a rare malignant neoplasm arising from soft tissue that produces osteoid, without any continuity to skeletal bones and constitutes 4% of osteosarcomas and 1.2% of all soft-tissue sarcomas [1,2]

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Summary

Background

Extraskeletal osteosarcoma (ESOS) is a rare malignant mesenchymal neoplasm in soft tissues but not directly attached to the skeletal system. Case history A 40-year-old woman was admitted to our hospital complaining of lower abdominal pain with nausea and vomiting for 4 days. She denied any history of other previous abdominal injuries or pain and had no other pertinent past medical history. The mass was located in the lower margin of greater omentum, and tumor invasion into surrounding organs was not observed. Abdominal CT revealed a large mass with mottled calcification and effusions in the peritoneal cavity (Figure 2). She died with widespread intra-abdominal, lung and liver metastases 7 months postoperatively

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