Abstract

Prevalence and Antibiotic Sensitivity Pattern of Methicillin- Resistant- Staphylococcus aureus in Kathmandu Medical College -Teaching Hospital

Highlights

  • Staphylococcus aureus is found to be a major source of community as well as hospital acquired infection

  • This study showed a high prevalence of MRSA in tertiary care hospital of Kathmandu valley

  • Present study conclusively shows that vancomycin remains the ¿rst choice of treatment for MRSA infection

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Summary

Introduction

Staphylococcus aureus is found to be a major source of community as well as hospital acquired infection. This study was undertaken to know the antibiotic sensitivity pattern of staphylococcal isolates with special reference to Methicillin resistant S. aureus. 5 undoubtedly accelerated the evolution of MRSA and led to the emergence of strains that have systematically acquired multiple resistance genes.[4] W ith the current emergence of multi-drug resistant MRSA in hospitals on the one hand[5] and the dramatically increased incidence of hyper-virulent community-associated MRSA on the other hand, MRSA has been able to evolve rapidly and create new clinical problems.[6] These strains are frequently implicated in serious infections and nosocomial outbreaks, which appear to be disseminated globally in adult, pediatric, and neonatal intensive care units (ICUs).[7]

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