Abstract
In this article we describe three cases reports about patients who were treated with progestins long time by different gynaecologic causes. Three patients started with neurological clinic and their imaging studies discovered intracraneal meningiomas of various sizes. All of them required treatment with combination of excision and stereotactic surgery. All of excised tumors showed positive staining for progesterone receptors of inmunohistochemical examination. Prolonged therapy with progesterone could promote the growth of benign intracranial meningiomas in some patients, indepently of doses and administration ways.
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