Abstract

Abstract3H‐ and 14C‐Labelled ethynodiol diacetate, chlormadinone acetate, and medroxyprogesterone acetate with one label at the steroid nucleus and the other at the acetoxy group were prepared for use in studies of regio‐ and stereospecificity of metabolic hydrolysis of the steroid contraceptives. Steroidal secondary, tertiary, equatorial, and axial acetates were labelled under selective conditions using acetic anhydride.

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