Abstract
The controlled-release tablets of sasanquasaponin (SQS) were prepared by using SQS, cornstalk and chitosan as the main drug and accessories. The effect of the particle size of cornstalk on release rate was studied. The thermal stability and wet stability of the controlled-release tablets of SQS were investigated. The controlled-release tablet of SQS was characterized by IR techniques. The releasing rate of the controlled-release tablets of SQS are controlled by controlling the particle size of cornstalk. The thermal stability and wet stability of the controlled-release tablets of SQS are good. The chemical bonds are formed among SQS, cornstalk and chitosan.
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