Abstract
PEG-PEI/Fe 3O 4 nano-magnetic fluids with different mass fractions of reactant were prepared by co-precipitation method. Besides particle size analyzer, the methods of XRD, IR, VSM and AFM were adopted to characterize the synthesized samples. Covalent bonding of PEG, PEI and Fe 3O 4 exhibits superparamagnetism. The TEM photograph shows that the particles are of stable dispersion and little aggregation, with smooth surface, spherical shape and a diameter of about 80 nm, which meets the requirements of nano-materials. When the mass fraction of PEI in reactant is 25%, the particle size, Zeta-potential and pEGFP-C1 DNA loading efficiency are all satisfactory. In this case, PEG-PEI/Fe 3O 4 nano-magnetic fluids can be used as gene vectors or targeted drug carriers.
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