Pre-Operative Diclofenac Sodium Eye Drops Vs Intra-Operative Adrenaline Irrigation in Maintaining Mydriasis during Extracapsular Cataract Extraction

Abstract

Purpose: To compare the effectiveness of pre-operative diclofenac sodium eyedrops with per-operative intraocular irrigation with adrenaline 1:1,000,000 (one inone million) solution in maintaining mydriasis during cataract surgery.Material and Methods: It was a randomized control trial and was conducted inthe department of Ophthalmology, Khyber Teaching Hospital Peshawar fromSeptember 2010 to March 2011. 210 patients with senile mature cataracts weredivided into two groups “A” and “B” with 105 patients in each group. Group “A”received pre-operative diclofenac eye drops for 24 hours and group “B” receivedper-operative irrigation with 1:1,000,000 of adrenaline solution. In all patientspupillary size was measured after cortical matter removal during extracapsularcataract extraction.Results: The mean age of patients in group “A” was 59.87 ± 6.54 SD years andin group “B” was 61.38 ± 6.30 SD. The mean pupillary size after cortical matterremoval in group “A” was 7.0667 mm ± 1.78 SD while that in group “B” was8.3371mm ± 1.94SD. The difference between the two was statistically significantafter applying independent sample„t‟ test with p value of <0.000.Conclusion: Per-operative irrigation of adrenaline 1:1,000,000 solution keepsbetter pupillary size as compared to pre-operative diclofenac sodium for patientsundergoing extracapsular cataract extraction,Key Words: Adrenaline, Extra capsular Cataract Extraction, Diclofenac sodium