Abstract
Development of resistant to most of commercially available anthelmintic became a sever problem worldwide. Pet ether, chloroform, ethyl acetate and methanol extracts of Acmella paniculata were evaluated for there anthelmintic activity using Pheretima posthuma model (Indian earthworm). The preliminary phytochemical analysis showed the presence of alkaloids, saponins, flavonoids and tannins in whole plant. Three concentrations (0.075, 0.15 and 0.22w/v) of each extracts were used for this study involve the determination of time of paralysis and time of death of the worm. Extracts obtained from whole plant not only paralyzed but also killed the earth worms. It was observed that both ethyl acetate, pet ether, chloroform and methanol extracts showed a remarkable Anthelmintic potential against intestinal parasitism. Further, there is scope to evaluate those active principles of Acmella paniculata whole plant for their Anthelmintic activity to open the new door for natural Anthelmintic.
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