Pregnancy-Associated Haemolytic Uraemic Syndrome

Abstract

Haemolytic Uraemic Syndrome (HUS) is a rare and severe form of thrombotic microangiopathy associated with a poor renal prognosis. Approximately 10-20% of the diagnoses of atypical Haemolytic Uremic Syndrome (aHUS) are related to pregnancy. Pregnancy acts as a trigger for aHUS, especially in the setting of preeclampsia and haemorrhage. It should be differentiated from other similar conditions such as severe preeclampsia, HELLP syndrome, and severe postpartum haemorrhage.