Abstract
Objective To investigate the clinical characteristics of severe preeclampsia complicated with AKI. Methods A retrospective study was conducted in 90 cases of severe preeclampsia complicated with AKI, who were admitted to the Third Affiliated Hospital of Guangzhou Medical University from August 2005 to July 2011. We studied the general condition, clinical characteristics and clinical outcomes of the patients. Results (1) The leading causes of severe preeclampsia complicated with acute kidney injury were severe postpartum hemorrhage, placental abruption, HELLP syndrome and kidney disease. (2) Patients with critical condition, the incidence of multiple organ dysfunction was 63.3%(57/90), and 58 (64.4%) cases admitted to the ICU. The total mortality was 15.6%(14/90). (3) With the increase of AKI stage, the curative rate was 71.9%(23/32)in stage I; 62.5%(5/8)in stageⅡand 28.0%(14/50)in stageⅢ; and AKIN criteria seem to have association with mortality. (4) The main causes of death for severe preeclampsia complicated with AKI included multiple organ dysfunction, cerebrovascular accident, severe postpartum hemorrhage and respiratory failure. Conclusions The main etiologies of severe preeclampsia complicated with acute kidney injury were severe postpartum hemorrhage, placental abruption, HELLP syndrome and kidney disease. The main causes of death for severe preeclampsia complicated with AKI included multiple organ dysfunction, cerebrovascular accident, severe postpartum hemorrhage and respiratory failure. Key words: Pre-eclampsia; Hypertension, renal; Pregnancy, high-risk
Published Version
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