Abstract
Globally, Tuberculosis (TB) remains one of the top ten causes of mortality. Furthermore, the incidence and prevalence of the disease spectrum remain high in low- and some middle-income countries. Due to the associated high morbidity and mortality, the World Health Organization (WHO) declared it a public health emergency. Furthermore, pulmonary cavitation, classified epidemiologically and clinically as the hallmark of TB, has been associated with increased bacillary burden, high infection transmission, and development of drug resistance.
Highlights
Tuberculosis (TB) remains one of the top ten causes of mortality [1]
The results of the primary analysis revealed that the crude odds ratio (OR) for the effect of TB multidrug resistance on pulmonary cavitation was 3.10
The non-adjusted OR for the role of rifampin, isoniazid, and ethambutol resistance, as ‘monodrug resistance’, on formation of pulmonary cavity are 4.26, 4.50, and 3.90, respectively
Summary
Tuberculosis (TB) remains one of the top ten causes of mortality [1]. the incidence and prevalence of the disease spectrum remain high in low- and some middle-income countries. Pulmonary cavitation, classified epidemiologically and clinically as the hallmark of TB, has been associated with increased bacillary burden, high infection transmission, and development of drug resistance [3,4] This complication has contributed to the persistence of TB worldwide and is further implicated in the high severity of the disease. Pulmonary cavitation, classified epidemiologically and clinically as the hallmark of TB, has been associated with increased bacillary burden, high infection transmission, and development of drug resistance.
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call