Abstract

Glandular Odontogenic Cyst (GOC) is a rare developmental odontogenic lesion with an aggressive behavior and a high recurrence rate. This study presents a case report of a 70-year-old Caucasian woman, who was referred to the Oral Diseases Diagnosis Center (Federal University of Pelotas), complaining of pain in the anterior mandible when chewing, which she had felt for approximately 9 months. Intraoral examination revealed a purple extensive swelling of the anterior mandible, with rupture of the cortical bone but with no tooth displacement. Panoramic and total inferior occlusal radiographs showed a well-defined multilocular radiolucency, extending from the first inferior right molar to the second inferior left molar. Histopathological analysis of an incisional biopsy revealed a cystic capsule lined by non-keratinizing stratified squamous epithelium, revealing areas presenting a papillary aspect, with superficial columnar cells, cilia, rare groups of mucous cells, and some clear cells. The diagnosis of GOC was confirmed. Due to the large size of the lesion and the risk of pathological fracture, marsupialization was performed. A significant decrease in the lesion and bone neoformation were observed after three months of follow-up. Complete curettage of the lesion has been planned, and the patient continues in rigorous follow-up.

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