GLANDULAR ODONTOGENIC CYST IN THE ANTERIOR MANDIBLE: AN UNUSUAL CASE

Abstract

Glandular odontogenic cyst (GOC) is an unusual entity, locally aggressive and with a high recurrence rate. A 60-year-old male patient was referred with the diagnosis of GOC from an incisional biopsy. Computed tomography revealed a hypodense unilocular lesion with cortical bone resorption involving the mandibular anterior region. After ostectomy, microscopic examination showed fragments of cystic capsule partially covered by epithelium of variable thickness, composed of cuboidal and columnar cells with papillary projections forming spherical nodules occasionally with the presence of cilia. Apocrine metaplasia was also seen, as well as clear cells in the epithelium basal layer. Additionally, intraepithelial microcysts and glandular spaces were observed. The diagnosis of GOC was made. After 4 months of follow-up, no recurrence was reported. Glandular odontogenic cyst (GOC) is an unusual entity, locally aggressive and with a high recurrence rate. A 60-year-old male patient was referred with the diagnosis of GOC from an incisional biopsy. Computed tomography revealed a hypodense unilocular lesion with cortical bone resorption involving the mandibular anterior region. After ostectomy, microscopic examination showed fragments of cystic capsule partially covered by epithelium of variable thickness, composed of cuboidal and columnar cells with papillary projections forming spherical nodules occasionally with the presence of cilia. Apocrine metaplasia was also seen, as well as clear cells in the epithelium basal layer. Additionally, intraepithelial microcysts and glandular spaces were observed. The diagnosis of GOC was made. After 4 months of follow-up, no recurrence was reported.