Botryoid odontogenic cyst versus glandular odontogenic cyst

Abstract

Üçok and associates recently reported a case of botryoid odontogenic cyst (BOC) presenting in the anterior mandible of a 32-year-old woman as a multiloculated radiolucent lesion extending from the left first premolar to the right first premolar in this journal 5 Üçok Ö. Yaman Z. Günham Ö. Üçok C. Dogan N. Baykul T. Botryoid odontogenic cyst: report of a case with extensive epithelial proliferation. Int J Oral Maxillofac Surg. 2005; 34: 693-695 Abstract Full Text Full Text PDF PubMed Scopus (15) Google Scholar . They correctly point out that BOC does not characteristically present as a multiloculated radiolucency; however, glandular odontogenic cyst often shows this radiographic pattern 4 Manor R. Anavi Y. Kaplan I. Calderon S. Radiological features of glandular odontogenic cyst (review). Dentomaxillofac Radiol. 2003; 32: 73-79 Crossref PubMed Scopus (46) Google Scholar . Üçok et al. provide a photomicrograph (Fig. 4) illustrating duct-like or glandular structures in the lining epithelium, a histological finding foreign to BOC but typical of glandular odontogenic cyst 3 Koppang H.S. Johannessen S. Haugen L.K. Haanæs H.R. Solheim T. Donath K. Glandular odontogenic cyst (sialo-odontogenic cyst): report of two cases and literature review of 45 previously reported cases. J Oral Pathol Med. 1998; 27: 455-462 Crossref PubMed Scopus (44) Google Scholar . They further report that lesional epithelium was positive for Ki-67 (MIB-1), a finding fully compatible with glandular odontogenic cyst 1 Kaplan I. Anavi Y. Manor R. Sulkes J. Calderon S. The use of molecular markers as an aid in the diagnosis of glandular odontogenic cyst. Oral Oncol. 2005; 41: 895-902 Abstract Full Text Full Text PDF PubMed Scopus (44) Google Scholar . Glandular odontogenic cyst, therefore, deserves serious consideration in the differential diagnosis 2 Kaplan I. Gal G. Anavi Y. Manor R. Calderon S. Glandular odontogenic cyst: treatment and recurrence. J Oral Maxillofac Surg. 2005; 63: 435-441 Abstract Full Text Full Text PDF PubMed Scopus (69) Google Scholar , 3 Koppang H.S. Johannessen S. Haugen L.K. Haanæs H.R. Solheim T. Donath K. Glandular odontogenic cyst (sialo-odontogenic cyst): report of two cases and literature review of 45 previously reported cases. J Oral Pathol Med. 1998; 27: 455-462 Crossref PubMed Scopus (44) Google Scholar and is probably a more appropriate diagnosis than botryoid odontogenic cyst.