Abstract
The natural gum Myrrh, a resinous extrude of genus Commiphora species, has found several applications, especially in traditional medicine. Myrrh has been used for treating different diseases, including inflammatory diseases, in diverse communities across the world. Allopathic usage of Myrrh, however, is limited by knowledge deficits regarding pharmacological mechanisms underlying these clinical effects, in particular, its anti-inflammatory role. This review aims to provide up-to-date information on the effect of myrrh extracts as well as its bioactive compounds on the functions of white blood cells and inflammatory mediators. Relevant information about the impact of Myrrh on the functions of white blood cells and inflammatory mediators was collected from established scientific databases such as NCBI, Web of Science, and Google Scholar. A few books were also referred to as obtaining important information. Myrrh and its bioactive molecules have been shown to have potential effects on the functions of white blood cells and immunomodulatory activities. However, few studies have reported these effects. In-depth studies are necessary to determine the effect of Myrrh and its bioactive molecules on immune cells and inflammatory mediators.
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