Population Pharmacokinetics of Sotorasib in Healthy Subjects and Advanced Solid Tumor Patients Harboring a KRASG12C Mutation from Phase 1 and Phase 2 Studies

Mario Nagase,Brett Houk,Irene Vuu,Panli Cardona,Sandeep Dutta,Chih-Wei Lin

doi:10.1208/s12248-024-01013-6

Population Pharmacokinetics of Sotorasib in Healthy Subjects and Advanced Solid Tumor Patients Harboring a KRASG12C Mutation from Phase 1 and Phase 2 Studies

Mario Nagase, Brett Houk + Show 4 more

https://doi.org/10.1208/s12248-024-01013-6

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Journal: The AAPS Journal

Publication Date: Jan 13, 2025

#Healthy Subjects #Advanced Solid Tumor Patients #KRASG12C Mutation #Solid Tumor Patients #Advanced Solid Tumor #Population Pharmacokinetics #Tumor Patients #Solid Tumor

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Population Pharmacokinetics of Sotorasib in Healthy Subjects and Advanced Solid Tumor Patients Harboring a KRASG12C Mutation from Phase 1 and Phase 2 Studies

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Population Pharmacokinetics of Sotorasib in Healthy Subjects and Advanced Solid Tumor Patients Harboring a KRASG12C Mutation from Phase 1 and Phase 2 Studies