Abstract

Objective To study the clinical features, diagnosis and treatment of polycystic liver disease (PLD) complicated with portal hypertension(PHT). Methods The clinical data of one patient with PLD and PHT was retrospectively analyzed, and relevant literature was reviewed. Results The patient presented fatigue,dyspepsia,abdominal distension and lower limb edema.Laboratory examination showed mild liver dysfunction(Alkaline phosphatase 291.2U/L,gamma glutamyl transpeptidase 168.1U/L,59.9g/L,total protein, albumin 32.2g/L,21.0μmol/L, total bilirubin,direct bilirubin 11.5μmol/L). Abdominal ultrasound(US)and computerized tomography(CT)showed multiple noncommunicating cysts of varying size in both liver and kidney. Antioxidant supplements and diuretic were introduced, and the therapy was approved to be effective. Conclusion The case in this report illustrates that PLD could occasionally present with PHT. Physician should be alert to prevent misdiagnosis. Key words: Polycystic liver disease; Polycystic kidney disease; Portal hypertension

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