Abstract
The pathogen diagnosis of infectious diseases plays a critical role in the rational application of antibiotics, the monitoring and management of disease epidemiology and the control of drug-resistant bacteria in hospitals and communities. The ideal method for rapid detection of infectious diseases should be sensitive, rapid, specific, stable, low-cost and easy to use. This article reviews the clinical application of POCT in infectious disease antigen detection, antibody detection, nucleic acid detection, etc. and focuses on the advantages and potential of microfluidic technology in pathogen multiplex nucleic acid detection and drug resistance detection. Choosing the right time, the right place, and the right on-site rapid diagnostic technology will provide a new strategy for the diagnosis and treatment of infectious diseases in the graded diagnosis and treatment mode. (Chin J Lab Med, 2018, 41: 641-643) Key words: Infections diseases; Point-of-care testing; Microfluidics; Microchip analytical procedures
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