Abstract
Objective: The present study aims at the preliminary phytochemical evaluation, gas chromatography–mass spectrometry (GC–MS) analysis, in vitro cytotoxicity, and anthelmintic activity of the hydroalcoholic extract of D. erecta leaves.
 Methods: The hydroalcoholic extraction of the plant material is done with Soxhlet apparatus and the GC–MS profiling of the extract is performed. The in vitro cytotoxicity activity of the extract is done using the MOLT-3 cell lines. The anthelmintic activity is performed using Pheretima posthuma. 
 Results: The GC–MS analysis shows the presence of various secondary metabolites with proved pharmacological activity. The in vitro cytotoxicity and the anthelmintic activity of the extract show the beneficial effect of the plant.
 Conclusion: The flavonoids, phenolic compounds, and tannins present in the plant extract may support the cytotoxic and anthelmintic activity of the plant.
Highlights
Duranta erecta is commonly known as “golden dew drops,” an ornamental plant
The preliminary phytochemical screening of the hydroalcoholic extract of D. erecta leaves shows the presence of tannins, phenolic compounds, steroids, glycosides, and flavonoids [13]
Retention time (RT), and molecular formula were used for the confirmation of phytochemical compounds
Summary
The hydroalcoholic extraction of the plant material is done with Soxhlet apparatus and the GC–MS profiling of the extract is performed. The in vitro cytotoxicity activity of the extract is done using the MOLT-3 cell lines. The anthelmintic activity is performed using Pheretima posthuma
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