Abstract

BackgroundMedicinal plants are of great importance to researchers in the field of pharmacology as most pharmaceutical industries depend on medicinal plant for their raw materials. Hibiscus asper belongs to the family Malvaceae and is well known for its medicinal properties. The present study was carried out to evaluate the antioxidant effect and possible bioactive components present in the aqueous methanol fraction of Hibiscus asper leaves.ResultsThe phytochemical of aqueous methanol fraction of Hibiscus asper leaves (AMFHAL) revealed the presence of flavonoids, tannin, phenols, saponins, alkaloids, glycosides, terpenoids, and steroids. The GC-MS analysis revealed the presence of twenty-three bioactive compounds which include 9,12,15-octadecatrien-1-ol, n-Hexadecanoic acid, octadecatrienol acid, methyl palmitate, and phytol.ConclusionThe phytochemical and GC-MS profiling of aqueous methanol fraction of Hibiscus asper leaves revealed the presence of bioactive compounds with important medicinal properties. Hence, the presence of these phytochemicals could be responsible for the therapeutic effects of the plant.

Highlights

  • Medicinal plants are of great importance to researchers in the field of pharmacology as most pharmaceutical industries depend on medicinal plant for their raw materials

  • Plants are used as medicines in various cultures and serve as a source of many potent drugs due to the presence of certain bioactive compounds for pharmaceutical industries [1]

  • Hibiscus asper Hook. f. (Malvaceae) is an important medicinal plant widely distributed in tropical Africa and Madagascar

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Summary

Introduction

Medicinal plants are of great importance to researchers in the field of pharmacology as most pharmaceutical industries depend on medicinal plant for their raw materials. Plants are used as medicines in various cultures and serve as a source of many potent drugs due to the presence of certain bioactive compounds for pharmaceutical industries [1]. The screening of plant extracts is a new approach to find therapeutically active compounds in various plant species [1, 5] The genus Hibiscus is made up of 250 species and is characterized by the presence of bioactive compounds such as phenolic acids, flavonoids, and polysaccharides [6] This plant is mostly used in folklore medicine for treatment of depression, jaundice, inflammation, anemia, dysmenorrhea, and leucorrhoea and as poison antidote [7]. It is used in the treatment of male infertility and skin infection and as an antioxidant [8, 9]

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