Abstract

Summary Following chemical characterization of the juvenile hormone (JH) of insects, synthetic optimization procedures created the first biorational products for insect control. Subsequently, the discovery of plant secondary chemistry possessing JH activity led to the development of a second generation of insect growth regulator products with enhanced efficacy. Phytochemical investigations also revealed compounds with antijuvenile hormone (AJH) activity suggesting additional biorational approaches for the disruption of insect metamorphosis and reproduction.

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