Photoacoustic Characterization of Cortical and Cancellous Bone in The Vertebrae.

Abstract

To date, spinal problems are not rare, and relevant therapies are always required. Although the combination of photoacoustic imaging (PAI) and spinal fusion surgery, a widely applied operation for spinal cures, is unprecedented, we assume that such combination might improve the accuracy and safety of the surgery. This paper aims to testify that PAI is effective in monitoring and navigating during spinal fusion surgery. Specifically, we examined the optical absorption spectrum of bones to determine the optimal laser wavelength as 532nm. Afterwards, we measured the photoacoustic signals of this bone samples, discovering that the signals of two kinds of samples, cortical bone and cancellous bone, differ considerably in frequency domain. It demonstrated the feasibility that PAI is effective enough to distinguish different bone tissues during the spinal fusion surgery.