Abstract
Immunization of Galleria mellonella larvae with filamentous fungus Aspergillus oryzae led to increase of phenoloxidase (PO) activity in hemolymph 24-72 h after treatment. In acidic/methanolic extracts of hemolymph collected from fungi-challenged insects additional peptide bands of molecular mass below 6.5 kDa were detected. When PO activity was determined in the presence of the extracts considerable decrease in the studied activity was noticed. We postulated that immune challenge of G. mellonella larvae with A. oryzae induced synthesis and/or release from storage compartments of peptides with inhibitory activity towards components of proPO system.
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