Pharmacognostical (Ingredient Analysis) and Pharmaceutical Evaluation of Yashtimadhu Taila (Glycyrrhiza glabra Linn.)

Abstract

Abstract Context: In Ayurveda, Yashtimadhu is being used as one of the healing drugs in the management of different kinds of wounds. The preparations made from Yashtimadhu such as Churna, Ghrita, Taila, and Malahar are being practiced in wound care unit to treat different kinds of wounds as local application. Multiple treatment modalities are mentioned in Sushruta Samhita for the management of various types of Vrana. Aim and Objective: This study was to standardize the finished product Yashtimadhu Taila to confirm its identity, quality, and purity. Yashtimadhu Taila is standardized using different parameters like pharmacognostical study including organoleptic characters such as color, odor, and taste. Subjects and Methods: Yashtimadhu Taila is prepared as per Sneh Kalpana mentioned in Sharangdhara Samhita. The pharmacognostical study includes organoleptic characters such as color, odor, and taste. The pharmaceutical study of Yashtimadhu Taila includes specific gravity, acid value, saponification, iodine value, and refractive index by the following standard procedures as per the Ayurvedic Pharmacopoeia of India, and chromatographic examination includes high-performance thin-layer chromatography (HPTLC) study. Results: All the physicochemical parameters show acid value (0.4883), saponification (178.7), iodine value (82.91), and refractive index (1.4820). HPTLC profile of the methanolic extract of the drug showed 14 spots at 254 nm and 8 spots at 366 nm. Conclusions: This study will be helpful to establish the safety profile, efficacy, and acceptance of classical parameters for further research studies.