Pharmaceutico-analytical standardization of Yashtimadhvadi Taila prepared from Murchhita and Amurchhita Tila Taila

Abstract

Introduction: Sneha Murchhana is a process carried out on fats and oils before subjecting to preparation of medicated ghee and oils. It can be interrelated to refinement of oil, though there is variation in refinement and Murchhana, that is, Murchhana enhances its concentration of high-density fatty acids, increases efficacy of formulation, and decreases rancidity and undesirable color. The standardization of Yashtimadhvadi Taila is not mentioned in Ayurvedic Pharmacopoeia of India; hence in this study, an attempt has been made to establish pharmaceutical standardization of Yashtimadhvadi Taila prepared from Murchhita and Amurchhita Tila Taila. Materials and Methods: For pharmaceutical standardization of Yashtimadhvadi Taila prepared from Murchhita and Amurchhita Tila Taila, Murchhana of oil was carried out as mentioned in Bhaishajya Ratnavali, and Yashtimadhvadi Taila was formulated as referred in Vaidya Chintamani. In analytical study, the samples were subjected to physicochemical analysis such as refractive index, specific gravity, saponification value, unsaponifiable matter, acid value, iodine value, and peroxide value. Observations: Average quantity obtained after Murchhana of Tila Taila was 94.74%, that is, 5.26% weight loss. Total time required for the preparation of MYT (Yashtimadhvadi Taila prepared from Murchhita Taila) and AYT (Yashtimadhvadi Taila prepared from Amurchhita Taila) was 10h and 8.30h with 7.29% and 5.20% weight loss, respectively. The heating process was finished in three days. After Murchhana, increase in saponification value and decrease in iodine and peroxide value were observed. This suggested that the application of Murchhana process on the base oil (Tila Taila) enhanced the properties and stability of Yashtimadhvadi Taila.Conclusion: Yashtimadhvadi Taila can be prepared in three days by heating and maintaining average temperature up to 100°C. Mild heating and constant stirring are needed for medicated oil preparations possessing desired attributes. Considering all the data of study indicates the importance of concept of Murchhana in the therapeutic potency of Yashtimadhvadi Taila.