Abstract
Thalassemia is one of the most challenging form of Haematological disorders. Gandhakadi Yoga is an Ayurvedic medicine comprising of SHUDDHA GANDHAKA (Sulphur), VIDANGA (Embelia ribes Burm.f.), AGASTYA PATRA (Sesbaniya grandifoliya Linn.), SHIGRU PATRA (Moringa Oleifera Lam.). Gandhakadi Yoga is a customized preparation of the formulation proposed for Loha Sevanajanya Vikara Prashamana (iron overloading) in Ayurveda Prakasha. here in Gandhaka and Vidanga are triturated with Agatsya patra Swarasa and then used therapeutically. So in the present study the formulation Gandhakadi Yoga has been selected for clinical evaluation on patients of Thalassemia Major, against the standard conventional approach (i.e. Blood Transfusion & Iron chelation therapy). The Pharmacognostical features of Gandhakadi Yoga Vati under the microscope observed that Oil globules, stone cell and Epicarp cells of Vidanga (Embelia ribesBur m.f.), Fragmented Unicellular Cell of Shigru, Simple Fiber of Shigru, Simple Trichome of Bhringraja base of Bhringaraja (E.alba.) and Crystaline depositions of Gandhaka were microscopically. Organoleptic features of finished product were within the normal range described in the classic.
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