PHARMACOECONOMIC ASPECTS OF HELMINTHIASIS TREATMENT IN PEDIATRICS

Abstract

The problem of parasitosis is quite pressing today, as the morbidity remains one of the most common in the world. According to the statistics, every third inhabitant of the planet is infected with one or another helminth, often 2-3 or even more of their species. In Ukraine 400-600 thousand patients with helminthiasis are registered each year, which is 53% of all infectious diseases, 80% of the identified patients are children. However, based on sales of anthelmintic drugs, the number of infected parasites can be several times higher. Objective - to optimize the reduction of helminthiasis treatment cost by conducting a pharmacoeconomic analysis of the anthelmintic drugs use. Material and methods. In order to monitor the state of the pharmaceutical market of antiparasitic drugs, we analyzed 83 medical records of inpatients (children aged 1 to 14 years) for worm infestations and medical records of medical institutions in Chernivtsi. Results. According to the results of pharmacoeconomic analysis "cost minimization", it was found that in the age category of 1-2 years while using a suspension of «Vormil» and «Zentel», there was no significant difference in the price of drugs for the treatment course. «Angelmex» (45%), «Vormil» (35%) and «Zentel» (15%) are used in the age group of 2-6 years. In the age group of 6-12 years, the choice of drug depends mostly on the dosage form, in 20% of cases more often they choose chewable tablets, due to the more comfortable way of use, regardless of the drug’s price. In the second stage of the research, a pharmacoeconomic analysis of the dietary supplements use for the helminthiasis prevention was performed. The cheapest for the treatment course was «Phytoglistocide» in the form of capsules (126,83 UAH) and syrup (275,88 UAH), and the most expensive - «Vormil Phyto» in the form of syrup (444,6 UAH). Conclusions. According to the results of the conducted researches it has been established that enterobiasis remains the most widespread in the Chernivtsi region area. Albendazole group agents in the form of tablets and suspensions are most commonly used in these helminthiasis treatment. The drugs of choice are «Algelmex», «Vormil», «Zentel», the choice of which depends on the age category.