Abstract
Corneal abrasion is the most frequent ocular complication to occur during the peri-operative period,Most abrasions are caused by lagophthalmos(failure of the eyelids to close fully)during general anaesthesia,resuhing in comeal drying. The most comon reason of ischemic optic neuropathy is the decreasing of optic nerve perfusion pressure lead to diminish of oxygen delivery in the choroid surrounding optic disk. Eye care with a lubricating ointment on a regular set schedule can effectively reduce the prevalence of corneal abrasions in patients who are either paralyzed or heavily sedated,and thus can help prevent serious complications.such as corneal ulceration,infection,and visual loss. Nanoparticles as a new vehicle for the improvement of the delivery of dnlgs to the ocular mucosa have been developed as a new continuous-delivery system for drugs that provide high and sustained levels of drugs to the cornea Key words: ocular injury; eye care; nanoparticle
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