Abstract
Hand sanitizer is a hand sanitizer antiseptic that is able to clean germs or viruses that stick to the hands. Most in the hand sanitizer market still use alcohol with a concentration of ±50%-70%. The use of alcohol in hand sanitizer is considered less safe for health because alcohol is an organic solvent that can dissolve the layer of fat and sebum on the skin that serves as a protector against infection of microorganisms. In addition, alcohol is also flammable and if repeated use on the hands will cause irritation. Research methods conducted in the determination of water content, the manufacture of hand sanitizer gel, pH measurement, viscosity and antimicrobials. Variations in carbpol concentration affect the physical properties and physical stability of the gel. Increased concentration of Carbpol increases the viscosity of the preparation. Based on the results of research conducted, it can be concluded that lime (Citrus aurantifolia) has the potential to inhibit the growth of microbes 1,0 x 101 colonies / g.
Highlights
ABSTRAK Hand sanitizer merupakan antiseptik pembersih tangan yang mampu membersihkan kuman atau virus yang menempel pada tangan
clean germs or viruses that stick to the hands
The use of alcohol in hand sanitizer is considered less safe for health because alcohol is an organic solvent
Summary
Formula yang dirancang pada penelitian ini adalah hand sanitizer berbentuk gel dengan penambahan Karbopol 0,5%. Pembuatan karbopol 0,5% yang diawali dengan mendispersikan karbopol ke dalam air sampai larutan koloid yang bersifat asam dengan viskositas rendah dan akan membentuk gel dalam viskositas tinggi. Pembuatan basis gel dilakukan dengan mendispersikan karbopol dalam air kemudian diaduk cepat untuk mencegah terjadinya aglomerat, kemudian dinetralkan dengan pembuatan TEA (trietanolamin) sebagai basa. TEA yang digunakan pada formulasi gel hand sanitizer sebanyak dua tetes karena jika terlalu banyak maka akan terbentuk gel yang sangat kental (Wijaya, 2013)
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