Abstract
Neem (Azadirachta indica) is a plant known for its wide array of therapeutic properties, derived from its diverse phytochemical makeup. Despite its medicinal benefits, neem can pose significant toxicity risks, especially in children. This report presents two pediatric cases of neem powder poisoning. The first case involves a two-year-old boy who ingested neem powder with milk, resulting in seizures and fatal cardiac arrest. The second case describes a six-year-old boy who experienced vomiting after consuming neem powder with milk. Prompt medical intervention, including gastric lavage and supportive care, led to his stabilization and discharge. Neem’s toxicity is attributed to compounds like azadirachtin, which disrupt mitochondrial function, leading to symptoms such as seizures, vomiting, and hepatic stress. These cases highlight the importance of recognizing the potential dangers of neem and underscore the need for public health education and regulatory oversight to prevent such adverse outcomes in pediatric populations.
Published Version
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