Abstract
Pathology of the organs of the hepatobiliary system, which happens in the form of calculous and non-calculous cholecystitis, cholangitis of various etiologies and other diseases of the biliary system, occupies one of the first places among surgical interventions on the organs of the abdominal cavity.
 Among the adult population, about 10% of those able to work suffer from gallstone disease. This disease is spreading in all countries of the world, and the tendency to its increase is growing. Such an increase in the pathology of the biliary tract is also observed in economically developed countries. Observations show that men suffer less often than women.
 The structure of the wall of the intrahepatic ducts is represented by the inner mucous membrane and the outer adventitia membrane. But the structure of their wall in different parts of the liver has its own characteristics. At the beginning of the intraciliary system of the liver, the mucous membrane is represented by epitheliolytic, which have a cubic shape.
 The outer shell is represented by cells of the fibroblastic series. In the average department of the internal biliary system of the liver, there is an increase in the size and number of cells in the inner lining of the ducts. Nuclei in the initial division change shape to a bean-like one. Changes in the inner membrane are observed in the terminal part of the intraciliary system of the sheep’s liver. Cells become prismatic and folds can be observed on their apical surface. Nuclei are localized on the basal surface and have a bean-like shape.
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