PD61-09 PREOPERATIVE LIPIODOL MARKING IMPROVED SAFETY AND SUCCESS RATE ON CT-GUIDED CRYOABLATION FOR SMALL RENAL MASSES

Abstract

You have accessJournal of UrologyKidney Cancer: Localized: Ablative Therapy1 Apr 2018PD61-09 PREOPERATIVE LIPIODOL MARKING IMPROVED SAFETY AND SUCCESS RATE ON CT-GUIDED CRYOABLATION FOR SMALL RENAL MASSES Fumiya Hongo, Yasuihro Yamada, Kenji Hiraoka, Munehiro Ohashi, Atsuko Fujihara, Koji Okihara, Kanji Miura, Kei Yamada, and Osamu Ukimura Fumiya HongoFumiya Hongo More articles by this author , Yasuihro YamadaYasuihro Yamada More articles by this author , Kenji HiraokaKenji Hiraoka More articles by this author , Munehiro OhashiMunehiro Ohashi More articles by this author , Atsuko FujiharaAtsuko Fujihara More articles by this author , Koji OkiharaKoji Okihara More articles by this author , Kanji MiuraKanji Miura More articles by this author , Kei YamadaKei Yamada More articles by this author , and Osamu UkimuraOsamu Ukimura More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.2833AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Partial nephrectomy for small renal mass (SRM) may be useful for preserving renal function, on the other hand, is technically more difficult than radical nephrectomy. Cryoablation can be performed under local anesthesia. Objective of this study is to assess the safety and therapeutic efficacy of cryoablation with lipiodol marking for SRM in the patients. METHODS Forty-two patients underwent cryoablation therapy under local anesthesia. Their median age was 74 years (31-91). The median tumor diameter was 21 mm (10-42). The response to treatment was evaluated using the mRECIST by contrast-enhanced CT in principle. In 6 patients (14.3%) in whom contrast medium could not be used, plain CT findings were assessed according to the RECIST. RESULTS Twenty-nine and 5 patients achieved complete response (CR) (69%) and partial response (PR) (12%), respectively, and 4 and 4 patients had stable disease (SD) (33%) and progressive disease (PD) (10%) after first therapy. In 3 of 4 patients with PD after the first therapy, second cryoablation with lipiodol marking was performed. Finally, 32 patients achieved CR (76%). PD was noted in 4 (36.4%) of 11 patients in whom lipiodol marking was not conducted, whereas none (0%) of 31 patients in whom lipiodol marking was conducted showed PD (p<0.01). Complications during a total of 45 sessions, 11 (24.4%) in all grade and 2 (4.4%) in grade 3 were observed. A significant difference was detected in the postoperative hemorrhagic events in all grade (18% in patients without lipiodol marking vs. 0% in patients without lipiodol marking (p<0.05)). CONCLUSIONS Although further studies involving more patients are needed to evaluate long-term results, cryoablation therapy seems to be a useful treatment option for SRM. Preoperative marking with lipiodol was helpful for improving complication and survival rates with cryoablation. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e1155 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Fumiya Hongo More articles by this author Yasuihro Yamada More articles by this author Kenji Hiraoka More articles by this author Munehiro Ohashi More articles by this author Atsuko Fujihara More articles by this author Koji Okihara More articles by this author Kanji Miura More articles by this author Kei Yamada More articles by this author Osamu Ukimura More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...