Abstract

As of 2020, the global prevalence of depression was approximately 246 million individuals; depression contributes substantially to the clinical, economic, and humanistic global burden of disease. The humanistic burden often includes impaired interpersonal relationships, decreased quality of life, and increased suicide risk. However, the burden extends beyond the patient with depression. Due to severe, long-lasting symptoms, depression can have a significant impact on caregivers and families and its presence in the progeny of afflicted parents can result in generational burden. This targeted literature review examined the caregiver burden and generational impact of depression.

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