Abstract

Purpose: To clarify characteristics of the routine examinations among the patients who show complex ventricular arrhythmias (CVA) during hemodialysis. Methods: Holter monitoring was performed in 18 chronic hemodialysis patients (12 male/ 6 female, mean 60.6 years old). Between the groups of patients with or without CVA during hemodialysis, various parameters including the patient's background and clinical examinations routinely investigated. Results: The background of the patients and clinical investigation revealed no significant difference between CVA+ and CVApatients. Both minimum systolic and diastolic blood pressure revealed difference between CVA+ and CVApatients (98.7±10.3 vs. 135.5±5.4mmHg; P<0.01). Moreover, mean (maximum systolic blood pressure-minimum systolic blood pressure) of CVA+ patients was significantly higher than that of CVApatients (42±8 vs 18±6 mmHg; P<0.05). Conclusion: The patients with CVA during hemodialysis have instability of blood pressure, which suggests their reduced arterial compliance, ventricular hypertrophy and low coronary perfusion. This work was supported by research grants from Ministry of Education, Culture, Sports, Science and Technology, Japan, and from the University of Tsukuba.

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