Abstract
We present four patients who suffered from malignant hypertension and recovered sufficient renal function to be withdrawn from dialysis. All of them were on continuous ambulatory peritoneal dialysis (CAPD) for varying periods of time, from four to 15 months, before dialysis could be suspended. Kidney size was relatively preserved except in one patient. Renal biopsy was performed in three patients: all showed some degree of acute tubular necrosis and hyperplastic arteriolitis, two showed fibrinoid necrosis; four to 20 % of glomeruli were sclerosed, there was no evidence of tubular atrophy or interstitial fibrosis. Blood Pressure (BP) control was achieved in all patients. Up to the last follow-up visit none of them had to come back for dialysis. We conclude that patients diagnosed as end-stage renal disease due to malignant hypertension should undergo a prudent period of strict BP control before being considered for transplantation because there is always the possibility of recovery of dialysisindependent renal function.
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