Pathologic changes in pig organs, infected with the Aujeszkys disease

V.V Ukhovskyi,O.M Romanov,B.V Borisevich

doi:10.15421/2020_199

Abstract

The data on histological studies of organs of suckling piglets that died from Aujeszky's disease presented in the article. To study of the microscopic changes, organ and tissue samples were taken from 5 suckling pigs (aged 4 to 6 days old). In all piglets, the diagnosis was confirmed by polymerase chain reaction. For histological studies, tissue samples were taken from the following organs: lungs, stomach, intestines, liver, pancreas, kidneys, thymus, lymph nodes, spleen, brain and spinal cord. The studies established that as a result of the Aujeszky’s disease virus impact on various organs and tissues, in dead pigs, significant pathomorphological changes are observed in most parenchymal organs. As a result of the histological studies of the internal organs of the pigs, died due to Aujeszky's disease the presence of significant microscopic changes in all morphological formations of these organs were found. It was described a number of micromorphological signs of piglets pathological changes and a set of criteria that can be used to substantiate a postmortem diagnosis of this disease was identified.

Highlights

IntroductionAujeszky's disease (pseudo-rabies) is contagious disease with acute course occurring in the form of epizootics and sporadic cases
Aujeszky's disease is contagious disease with acute course occurring in the form of epizootics and sporadic cases
As a result of the virus impact on various organs in animals that have died or been ill with Aujeszky's disease, significant pathological changes were observed in magority of a parenchymal organs (Lai et al, 2019; Tong et al, 2020)

Summary

Introduction

Aujeszky's disease (pseudo-rabies) is contagious disease with acute course occurring in the form of epizootics and sporadic cases. As a result of the virus impact on various organs in animals that have died or been ill with Aujeszky's disease, significant pathological changes were observed in magority of a parenchymal organs (Lai et al, 2019; Tong et al, 2020). When the virus penetrates the skin, its enhanced reproduction occurs at the infected area with changes of the blood chemical composition with increasing of the acetylcholine and histamine contents in the central nervous system and skin changes, causing the development of hyperesthesia (itching) (Miller et al, 2019; Sorooshyari et al, 2018 ; Wong et al, 2019). The study of histological changes in the internal organs of suckling piglets, due to the significant variability of the etiological factor of this disease, namely Suid alphaherpesvirus 1 had the particular relevance (Minamiguchi et al, 2019; Moreno et al, 2015)

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