Palladium-catalyzed cross-coupling reactions of arylboronic acids and 2-I- p-carborane

Abstract

p-Carborane has been arylated on the 2- B-atom in high yields, using the Suzuki–Miyaura reaction. Thus the reaction between 2-I- p-carborane and various arylboronic acids [1-naphthyl-, phenyl-, 4-MeOC 6H 4, 3-CH 3CONHC 6H 4, 4-NCC 6H 4, 3-NO 2C 6H 4], gave the corresponding 2-aryl- p-carboranes in DME solution when reacted in the presence of cesium fluoride and the catalytic Pd 2(dba) 3–dppb system.