P-760: Evidence that high serum progesterone (P) levels on day of human chorionic gonadotropin (hCG) injection have no adverse effect on the embryo itself as determined by pregnancy outcome following donor embryo transfer

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There is evidence that a premature rise in P on the day of hCG injection has an adverse effect on pregnancy rates following in vitro fertilization-embryo transfer (IVF-ET). The objective of the present study was to determine pregnancy outcome in recipients according to the P level of the donor at the time of hCG injection. Lower pregnancy rates with advancing P levels would suggest that the adverse effect of P is on the embryo itself. No adverse effect at most levels of elevated P would suggest the adverse effect was on the endometrium.