Optimal extracting technique of Baipuhuang capsules by orthogonal test

Abstract

Objective To optimize the extracting technique of Baipuhuang capsules. Methods The extraction technique of Radix Scutellariae, dandelion, and radix Pulsatillae in Baipuhuang ingredients was optimized by the orthogonal test with the extract yield, the yield of Baicaline as indexes. Results The optimum extracting technique for these three kinds of medicinal materials was crushed into coarse powder, adding eightfold amount of 80% ethanol reflux extraction 3 times, each time for 1.5 hours. Conclusions The process is better than the original tablets, extract yield is low, high metastasis rate of effective components, and the results provide the conditions for preparation of Baipuhuang capsules. Key words: Baipuhuang capsules; Orthogonal test; Extracting technique