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https://doi.org/10.1007/bf00156368
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Cite Journal: Biotechnology Techniques |  Publication Date: Dec 1, 1993 |
 Citations: 25 |
Affiliation: Imperial College London, University College London
A computer-based algorithm was used for the open-loop control of specific growth rate in fed-batch cultures of recombinant E.coli.. The control of nutrient feed rate to an exponential trajectory resulted in growth of the culture at a constant specific growth rate. Stable specific growth rates between 0.08 and 0.4 h−1 were achieved.
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