Abstract
The reciprocating size exclusion chromatography (RSEC) was operated with swing between two temperatures in a synchronous way with flow direction to recover a large solute on-line from the mixture, in addition to the small solute concentration. The concentration of small solutes in RSEC with a temperature swing was made possible by taking advantage of the temperature-dependent swelling properties of the porous gel. After 7 cycles of frontal mode operation, 76% of Blue Dextran in the feed was recovered and nickel nitrate in the feed reservoir was concentrated by 13%.
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