Abstract

This research aims to develop a novel way for synthesizing indole derivatives. 1-(phenyl)-1H-indole analogues were synthesized by cyclization of 1-phenyl-2-(phenyl amino)-ethane-1-one. Biological evaluation of title compounds and absorption, distribution, metabolism and excretion (ADME) studies were performed and title compounds had a higher affinity and created ample interactions with different proteins.

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