Oncothermia Basic Research at In Vivo Level: The First Results in Japan

Abstract

This paper summarizes the first results of oncothermia basic research conducted in Tottori University, Japan, and had two parts. In the first part C26 murine colorectal cancer model was investigated and oncothermia treatment induced histomorphological and some molecular changes which were examined. In the second study 9L rat glioma model was used to investigate the oncothermia treatment effects on tumor tissue oxygenization. Results of these investigations are very important in oncothermia research because this was the first time when independent research laboratory has repeated oncothermia experiments and proved the significant antitumoral and beneficial effects of oncothermia treatment.