Abstract
Calcium oxy fluoro borophosphate glasses doped with fixed concentration of Fe2O3 and mixed with different important modifier oxides (viz., BaO, SrO, ZnO and MgO) that play a crucial role in healing bone fractures and in improving osteointegration etc., were synthesized. In vitro bioactivity studies were carried out by immersing the samples in simulated body fluid (SBF) solution for about one month. The formation of HAp layer on the surface of the samples was confirmed by recording XRD and SEM photographs and also IR spectra before and after immersion in SBF. The magnitude growth of HAp layer was evaluated by measuring weight loss of the samples along with pH measurements of the residual solutions at specific intervals of time. The analysis of the results of degradability together with spectroscopic studies viz., IR and optical absorption spectra have revealed that BaO is an effective modifier in improving the bioactivity of the host glass, among all the modifiers investigated.
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