Occurrence and risk of chlorinated polyfluoroalkyl ether sulfonic acids (Cl-PFESAs) in seafood from markets in Beijing, China

Abstract

In recent years, chlorinated polyfluoroalkyl ether sulfonic acid (Cl-PFESA, trade name: F-53B), one of the alternatives to perfluorooctane sulfonate (PFOS), has been widely detected in environmental matrices and organisms in China. However, sufficient information regarding its presence in seafood is not available. Therefore, we investigated the levels of Cl-PFESAs and legacy per- and polyfluoroalkyl substances (PFASs) in 276 seafood samples collected from markets in Beijing and assessed the human exposure risks of Cl-PFESAs through seafood intake. C8 Cl-PFESA was the dominant congener with significantly higher concentrations (<LOD–1.27 ng/g) than those of C10 Cl-PFESA (<LOD–0.109 ng/g) and C12 Cl-PFESA (<LOD–0.141 ng/g). The mean concentrations of ∑Cl-PFESAs (0.013–0.412 ng/g) contributed to 0.6–11.4% for ∑PFASs in different seafood species. Generally, the concentrations of C8 Cl-PFESA were lower than those of PFOS. However, their concentration trends in four categories of seafood were consistent, with the highest mean concentrations being in shrimps (0.279 and 0.749 ng/g), followed by crabs (0.275 and 0.714 ng/g), fish (0.141 and 0.317 ng/g), and mollusks (0.032 and 0.135 ng/g). A significantly positive correlation was observed between the concentrations of C8 Cl-PFESA and PFOS in all seafood samples (p < 0.001), indicating that they have similar sources and undergo similar environmental processes. The average daily intake of C8 Cl-PFESA (0.067 ng/kg-bw/day) for residents in Beijing via the consumption of seafood was lower than that of PFOS (0.167 ng/kg-bw/day) and far below the most stringent health-based reference dose of PFOS (1.86 ng/kg-bw/day), which implies a low risk for Beijing residents exposed to C8 Cl-PFESA by ingestion of seafood. However, considering the omnipresence of Cl-PFESAs and their stronger bioaccumulation than PFOS, further study on the potential environmental and human exposure risks of Cl-PFESAs is required.