Observation on effects of compound glycyrrhizin combined with glucophage intervention in treatment of nonalcoholic fatty liver disease and prognosis

Abstract

Objective To explore and analyze the clinical curative effect of compound glycyrrhizin combined with glucophage intervention to nonalcoholic fatty liver disease prognosis.Methods In our hospital from May 2012 to March 2013 in outpatient medical centers and hospital treatment,80 patients with nonalcoholic fatty liver were divided into the treatment group and the control group,40 cases in each,depending on the treatment,the control group was given only compound glycyrrhizin,3 times/d,2 tablets/time.Treatment group was added glucophage on the basis of the control group,500 mg/time,3 times/d,with the total course of 3 months.Effects were observed.Results The treatment group was 85％,60％ in the control group,showing statistical significant difference,P＜0.05; after treatment,blood lipids and liver function indicators difference were also statistically significant P＜0.05.After treatment,the fatty liver CT value of two groups showed a statistical significant difference,P＜0.05.Conclusion The compound glycyrrhizin combined with glucophage intervention has significant efficacy in treatment of nonalcoholic fatty liver prognosis,and should be widely applied. Key words: Compound glycyrrhizin; Glucophage; Nonalcoholic fatty liver disease