Observation of ropivacaine combined morphine or fentangl for controlled epidural analgesic on intestinal peristalsis

Abstract

Objective To investigate the effects of patient controlled epidural analgesic(PCEA) used ropivacaine and different analgesic drugs on recovery of postoperative intestinal peristalsis.Methods 105 patients of abdominal surgery undergoing selection operating,ASA Ⅰ,Ⅱ grade.Every section was randomly divided into three groups according to the content of drugs.Morphine group:0.125％ ropivacaine + 0.005％ morphine + 0.005％ droperidol.Fentanyl group:0.125％ ropivacaine +0.0005％ fentanyl +0.005％ droperidol.Control group is not used PCEA.All patients were taken PCEA for 36 hours.The pain scores of visual analog scale ( VAS),sedative scores of Ramsay scale,respiratory and hemodynamic paremeters,and side effects were recorded at 4,8,12,24,36 hours postoperatively.The time of the recovery of intestinal peristalsis was also recorded.Results Good analgesic effect could be found in morphine group and fentanyl group,the VAS grades were significantly lower in morphine group and fentanyl group than that in control group( P ＜ 0.01 ).The time of the recovery of intestinal peristalsis was shorter in fentanyl group than that in morphine group and control group respectively ( P ＜ 0.05 ).Conclusion Compound solution with low concentration of ropivacaine and morphine or fentanyl can be used for postoperative analgesia,and ropivacaine combined with fentanvl can shorten the time of the recovery of intestinal peristalsis. Key words: Gastrointestinal motility; Morphine; fentanyl; Ropivacaine