Observation of controlled hypotension induced with remifentanil nitroglycerin in endoscopic sinus surgery

Abstract

Objective To observe the effects of controlled hypotension induced with remifentanil nitroglycer- in in endoscopic sinus surgery. Methods 60 ASA I - Ⅱ patients treated with endoscopic sinus surgery were random- ly divided into 3 groups：general anesthesia（ group A）, nitroglycerin （group B）, remifentanil nitroglycerin group （group C）. The blood pressure, heart rate, the quality of the surgical field, surgical time, extubation time, blood loss and sur- geon satisfaction of the surgical field were observed during anesthesia. Results The operative time showed statistic significance between the groups （F = 4. 792, P 〈 0.05）.＇In terms of the extubation time, there was a statistically sig- nificant difference between the groups （ F = 37. 507, P 〈 0.01 ）. The blood loss and the quality of the surgical field were statistically significant between the groups respectively （ F = 16. 011, P 〈 0.01 ; F = 71. 050, P 〈 0.01 ）. Conclusion Controlled hypotension induced with remifentanil nitroglycerin in endoscopic sinus surgery can lower blood pressure effectively, improve the quality of surgical field, and shorten the operation time and the extubation time. Key words: Remifentanil; Nitroglycerin; Controlled hypotension; Endoscopic sinus surgery