Application of dexmedetomidine inducing controlled hypotension in functional endoscopic sinus surgery

Abstract

Objective To investigate the security and efficacy of dexmedetomide inducing controlled hypotension in functional endoscopic sinus surgery.Methods Sixty patients subjected to general anesthesia were divided into two groups:the nitroglycerin group(group N) and the dexmedetomidine group (group D).The MAP was maintained at 60-70 mm Hg(1 mm Hg =0.133 kPa).The quality of the surgical field was assessed and the HR,MAP was recorded during operation; Amount of bleeding,urine volume,and adverse raction were recorded.Results The MAP was maintained at 60-70 mm Hg in all patients.The quality of the surgical field was better in the group D;Rebound hypertension occurred in the group N when extubating,the MAP was still lower than the level of preinduction in group D.Amount of bleeding was fewer and amount of urine volume was more in the group D.There were two patients agitated after operation in the group N and there was no other postoperative complication in all patients.Conclusions Induced hypotension by dexmedetomidine is feasible and safe in the functional endoscopic sinus surgery. Key words: Dexmedetomidine; Controlled hypotension; Endoscopic sinus surgery; General anesthesia ; Nitroglycerin