Abstract
ObjectiveTo compare reproductive outcomes in our in vitro fertilization (IVF) program according to women's body mass index (BMI). Subjects and methodsWe included a total of 863 IVF-intracytoplasmic sperm injection (ICSI) cycles with controlled ovarian stimulation with GnRH antagonists. ResultsPatient age differed among the BMI groups but this difference was not clinically relevant (± 1 year). No significant differences were found among BMI groups in the duration of ovarian stimulation or in the total follicle-stimulating hormone dose used. However, there were significantly fewer selected follicles, retrieved oocytes, mature oocytes and transferred embryos at higher BMIs. Rates of pregnancy and live births were progressively and significantly reduced as BMI increased (group i: 41.4%, group i: 32.5%, group iii: 29.6%; P<.05). ConclusionsFemale overweight and obesity impair IVF outcomes. Pregnancy and live birth rates were progressively reduced as BMI increased.
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